{"id":2444,"date":"2023-02-23T12:52:06","date_gmt":"2023-02-23T11:52:06","guid":{"rendered":"https:\/\/www.beachemie.com\/?post_type=maerkte&#038;p=2444"},"modified":"2026-07-17T11:56:35","modified_gmt":"2026-07-17T09:56:35","slug":"infusionsfluessigkeiten","status":"publish","type":"maerkte","link":"https:\/\/beachemie.com\/en\/maerkte\/pharma\/infusionsfluessigkeiten\/","title":{"rendered":"Infusion Liquids and Injectables"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"2444\" class=\"elementor elementor-2444\" data-elementor-post-type=\"maerkte\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6553a6c2 e-flex e-con-boxed e-con e-parent\" data-id=\"6553a6c2\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-97ebba2 e-con-full e-flex e-con e-child\" data-id=\"97ebba2\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-45e1e4cc elementor-widget elementor-widget-text-editor\" data-id=\"45e1e4cc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>In large-volume parenterals (LVPs) and small-volume injectables, acetate salts serve as critical physiological buffers and metabolic precursors, offering a safer alternative to other standard anions.<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-40ec3697 elementor-widget elementor-widget-heading\" data-id=\"40ec3697\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Physiological buffering and metabolic support<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-646a339e elementor-widget elementor-widget-text-editor\" data-id=\"646a339e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>While bicarbonate (HCO\u2083\u207b) is the body's natural blood buffer, it cannot be readily used in all formulation concentrates or infusion bags because it tends to precipitate with calcium or magnesium and can release CO\u2082, thereby altering the solution's pH.<\/p><p>Sodium acetate trihydrate acts as a stable, highly soluble alternative.<\/p><p>Once infused, it is metabolized by the liver, muscles, and peripheral tissues into bicarbonate on a 1:1 molar basis, safely correcting metabolic acidosis without compromising formulation stability.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-73def9dc elementor-widget elementor-widget-heading\" data-id=\"73def9dc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Balanced electrolyte solutions<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-44ca5959 elementor-widget elementor-widget-text-editor\" data-id=\"44ca5959\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Prolonged infusion of standard saline solutions can lead to hyperchloremic metabolic acidosis due to an excess of chloride ions.<\/p><p>To mitigate this risk, modern balanced electrolyte solutions (e.g. Ringer's Acetate) replace part of the sodium chloride with sodium acetate trihydrate. Furthermore, potassium acetate, magnesium acetate tetrahydrate, and calcium acetate are used in customized pharmaceutical formulations to provide essential macro-minerals in a chloride-free matrix.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"featured_media":3313,"parent":2443,"menu_order":7,"template":"","produkte":[],"class_list":["post-2444","maerkte","type-maerkte","status-publish","has-post-thumbnail","hentry","wpbf-post"],"acf":[],"_links":{"self":[{"href":"https:\/\/beachemie.com\/en\/wp-json\/wp\/v2\/maerkte\/2444"}],"collection":[{"href":"https:\/\/beachemie.com\/en\/wp-json\/wp\/v2\/maerkte"}],"about":[{"href":"https:\/\/beachemie.com\/en\/wp-json\/wp\/v2\/types\/maerkte"}],"version-history":[{"count":5,"href":"https:\/\/beachemie.com\/en\/wp-json\/wp\/v2\/maerkte\/2444\/revisions"}],"predecessor-version":[{"id":4571,"href":"https:\/\/beachemie.com\/en\/wp-json\/wp\/v2\/maerkte\/2444\/revisions\/4571"}],"up":[{"embeddable":true,"href":"https:\/\/beachemie.com\/en\/wp-json\/wp\/v2\/maerkte\/2443"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/beachemie.com\/en\/wp-json\/wp\/v2\/media\/3313"}],"wp:attachment":[{"href":"https:\/\/beachemie.com\/en\/wp-json\/wp\/v2\/media?parent=2444"}],"wp:term":[{"taxonomy":"produkte","embeddable":true,"href":"https:\/\/beachemie.com\/en\/wp-json\/wp\/v2\/produkte?post=2444"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}